Post Graduate Diploma/Executive Diploma in Drug Discovery and Development

IGMPI

The drug needs are changing rapidly and so is increasing the need of technically and professionally trained individuals with sound knowledge scientific attributes related to the field. The academic training in drug development forms the base but they need to be backed with professionals training. IGMPI serves this purpose well with its online learning programme in drug development and discovery.

The programme trains and guides the candidate through varied aspects of this industry to ensure a complete all round grooming of the aspirant. Producing only efficient and productive professionals for the industry is the only concern of this professional programme. Post Graduate Diploma/Executive Diploma programme by IGMPI adds to the candidate’s potential of entering into this industry by offering:

• Complete knowledge of the theoretical chapters (structural design, rational and combinatorial methods, drug target selection, etc.)
• Knowledge and training of practical drug designing tools
• Application and technicalities of drug development process
• Guidance by field experts during the programme and drug patenting
• Knowledge of global scenarios, scope and opportunities.
• Knowledge about the clinical trials, ethics and regulatory processes involved.

IGMPI programme promise to polish the skills of its candidates and make them job ready! The candidates are taught the techniques, given practical knowledge and accustomed to the varied on-field situations that might arise during their careers. All this is made possible with help of:

• Extensive programme material which has been designed by experts who are or have been contributing to the industry in the past;
• Numerous case studies which are a part of the programme;
• Intelligently aligned programme structure which gives step wise knowledge and insight of the industry and all its aspects.

Programmme Structure :

Module 1: Introduction to Drug Design and Development

Introduction to Drugs, Names of Drugs, Types of Drugs

Drug Discovery Process: General Introduction, Flow of Drug Discovery Process

Module 2: Cellular and Molecular Biology

Structure and Function of Cell

Cell Cycle, Cell Division and Cell Death

Biomolecules: Nucleic Acids, Proteins, Carbohydrates and Lipids

Receptors and Secondary Signalling

Module 3: Concepts of Pharmacology

Introduction to Pharmacology

Routes of Administration

Pharmacokinetics: Absorption, Distribution, Metabolism and Excretion

Pharmacodynamics: Drug-Receptor Interaction and Terminologies

Module 4: Modern Drug Discovery Process

Target Identification and Validation

Lead Identification and Optimization

Economics of Drug Discovery

Role of Genomics, Proteomics and Bioinformatics

Role of Nucleic acid Microarrays, Protein microarrays, Antisense Technologies, siRNAs, Antisense Oligonucleotides, Zinc Finger Proteins

Role of Transgenic animals in Target Validation

Module 5: Lead Identification

Combinatorial Chemistry and HTS

In silico Lead Discovery Techniques

Assay Development for Hit Identification

Proteins: Structure and Functions

Domains, Motifs and folds in Protein Structure

Computational Prediction of Protein Structure: Threading and Homology modeling methods

Applications of NMR and X-ray in Protein Structure Prediction

Module 6: Rational Drug Design

Traditional vs. Rational Drug Design

Methods in Traditional Drug Design

Concepts of Rational Drug Design

Methods in Rational Drug Design: Structure and Pharmacophore based approaches

Virtual Screening Techniques: Drug Likeness screening, Concepts of Pharmacophore mapping and Pharmacophore based Screening

Module 7: Molecular Docking

Rigid Docking, Flexible Docking & Manual Docking

Docking Based Screening

De novo Drug Design, Quantitative Analysis of Structure Activity Relationship, History and Development of QSAR, SAR vs. QSAR

Physiochemical Parameters: Hansch Analysis, Fee Wilson Analysis and relationship between them

Module 8: QSAR Statistical Methods

Regression Analysis, Partial Least Square Analysis (PLS) and other multivariate statistical methods

3D-QSAR approaches: COMFA & COMSIA

Module 9: Pro-drug based Concepts

Prodrug Design-Basic Concept

Prodrugs to Improve Patient Acceptability

Drug Solubility, Drug Absorption and Distribution, Site-specific Drug Delivery & Sustained Drug Action

Rational of Prodrug Design

Practical Consideration of Prodrug Design

Module 10: Biostatistics in Drug Discovery and Development

Defining the Research Problem

Sampling Design

Hypothesis testing

Parametric and Non parametric test

Scientific Writing

Module 11: Pharmacological and Toxicological Screening Methods

General Principles of Screening and Animal Models

Pharmacological Screening Models – Hypertension, Pain, Epilepsy, Depression, Ulcers, Ischemia, Alzheimer’s disease, Parkinson’s disease, Diabetes and Leishmaniasis.

Regulatory Toxicology (OECD Test Guidelines: Acute, Sub-acute, Sub-chronic & Chronic, Reproductive Toxicity, Teratogenicity, Genotoxicity and Carcinogenicity

Module 12: Introduction to Clinical Research and Pharmacovigilance

Clinical Trials

Clinical Research Stakeholders and Core team

Ethics in Clinical Research

Pharmacovigilance

Seriousness, Expectedness and Casualty Assessment of ADRs

PvPI

Module 13: Demonstration of Instrument Handling and Analytical Techniques

Module 14: Industry Based Case Study

Eligibility

Any Graduation/ B.tech/ B.Sc. in Microbiology/ Life Sciences/ Botany/ Zoology/ Food Science/ Food Technology/ BE/ B.Pharma/ MBBS/ BDS/ BHMS/ BUMS/ BAMS or any other discipline. Diploma holders are eligible for our Executive Diploma, Industry Certificate, and Certificate Programmes.

Programme Duration

The duration to complete this programme is 1 year (Post Graduate Diploma), 6 months (Executive Diploma).

Registration

The registration dates for this programme run by the Institute are updated timely on the webpage. Effective online learning tools incorporated into the design of the webpage make the programme lectures, online live classes and study material easily accessible. This gives a huge window of self-regulated and self-paced performance to the participants.

Programme Deliverables

A comprehensive study material for all the modules in hard copies ensuring the needs of the audience. The accompanying training material is appropriately aligned with the current Industry’s expectations.

– Assignments for all the programme modules for continuous evaluation and guidance.
– Interactive or online live sessions on all key areas of the programme giving all flexibility to the participants.
– Online classes for all the modules will be conducted on the weekends. Moreover, a doubt clearing session will also be scheduled before the examination.
– All the efforts are made by IGMPI faculty members to make the entire programme modules easily understandable.
– Assessment and evaluation for all the programme modules in order to enhance the levels of competencies and skills of the participants leading towards the objective of application in the job.
– At the end of each programme modules, the trainers shall obtain feedback from the participants using specially designed questionnaires.
– All learning and training delivery initiatives shall be conducted in English.

Examination & Certification

IGMPI follows a credit system based on all learning activities involved in studying for all PG Diploma, Executive Diploma and Certificate Programmes. Each of your modules is equal to 4 credits. To successfully complete the programme, you will have to earn all the credits assigned to your programme. This programme is approved by Quality Council of India (QCI), Government of India.

All the participants are obliged to timely submit completed assessment assignments (during the programme, usually after every module) and appear for an online exam at the end of the programme. After successful completion, the participants will be awarded Post Graduate Diploma/Executive Diploma in Drug, Discovery and Development by Faculty of Drug Discovery and Development, IGMPI. For all the above-mentioned modules, Online Classes (Online mode) or face-to-face classes (Regular mode), elaborate programme material, self-assessment assignments would be provided by the Institute. Details get updated on the webpage as well.

Placement Assistance & Corporate Relations

The Institute has partnered with many organizations for providing with placement assistance to its participants. Besides, it has a robust placement cell comprised of senior level Human Resources professionals and Talent Acquisition experts which maintains close links with business and industry. This cell is continuously engaged in promoting the employability of our participants and encouraging the concerned Human Resources department and Hiring Managers to recruit/hire our participants for their vacant positions. The efforts of our placement cell also include helping with professional resume writing & interview skills.

In recent months the Institute has witnessed more and more participation from professionals working with global pharmaceutical like Mankind Pharma Ltd., GSK, Syngene International, IPCA Laboratories, GVK Biosciences, Aurobindo Pharma Ltd., Gland Pharma Ltd., Dr. Reddy’s Laboratories, Ranbaxy, Torrent Pharmaceuticals, Wockhardt Ltd., Piramal Life Science, Alembic Ltd., Zydus Cadila, Cadila Pharmaceuticals, FDC Ltd., JB Chemicals & Pharmaceuticals, Cipla, Glenmark Pharmaceuticals, Lupin Ltd., Orchid Pharma, Natco Pharma, Matrix Laboratories, Hetro Drugs, Jubilant Life Sciences, etc. The IGMPI’s Corporate Resource Division actively recommends our students and training participants for various job requirements and specialized roles to Human Resource, Talent Acquisition as well as the heads of various departments in Pharmaceutical, Healthcare industries on regular basis.

Future career prospects of Training in Drug Discovery and Development

Professionals in this industry have a global standing and responsibility as well. The work done here serves to global audience and is not just country specific. Thus, the field beholds immense respect for its takers which comes with equal amounts of pressure to ensure proper code and ethics of the field are followed. IGMPI offers comprehensive training in drug discovery and development which is essential; for ensuring a benefitting future in the industry. Pass outs from this programme are eligible to find work in:

• Pharmaceutical companies,
• Biomedical companies,
• Technology/consulting companies in the healthcare arena or even government sector.

The programme also prepares for positions and roles like Medicinal chemist, Computational chemist, Nano Technician or In Silico Drug Designer. IGMPI offers professional and industry oriented training thus opening doors for entry into the industry. Post Graduate Diploma/Executive Diploma in Drug discovery and Development adds advantage for those already in the industry as a tag of professional training and those new to the industry feel comfortable with backing of apt and up-to-date information and training required to have sustained growth in the industry.

View Prospectus

Programme Fee Details

How to apply

For further enquiries, write to or call us on:
info@igmpi.ac.in/ 18001031071 (Toll Free) , Phone: +91 11 26512850